How to fight against urban pollution with lime extract

Time: 10:10 - 10:30

Date: 21 Novembre 2018

Theatre: Green 1

21-11-2018 10:10 21-11-2018 10:30 Europe/London How to fight against urban pollution with lime extract

Pollution is present everywhere in urban areas. It is composed of pesticides, heavy metals, particles and other harmful chemicals that will disrupt skin barrier function and microbiota. Pollution will produce several intracellular damages by oxidative stress, activation of mitochondrial AhR, ATP production decrease and inflammation. To fight against this daily aggression, BIOLIE has developed a… Leggi tutto »

Making Cosmetics

Pollution is present everywhere in urban areas. It is composed of pesticides, heavy metals, particles and other harmful chemicals that will disrupt skin barrier function and microbiota.

Pollution will produce several intracellular damages by oxidative stress, activation of mitochondrial AhR, ATP production decrease and inflammation.

To fight against this daily aggression, BIOLIE has developed a lime extract thanks to its enzymatic extraction process. This lime extract, rich in citroflavonoids and saccharides, has been tested on urban pollution using an original test on keratinocytes with URBAN DUST (NIST® SRM® 1649b). URBAN DUST, approved by FDA, is representative of urban pollution, including all type of molecules (not only heavy metals or particles). The test evaluates pollution impact on keratinocytes DNA by the comet method.

Our results showed that Urban pollution significantly increased (by 100%, P<0.05%) keratinocyte’s DNA damage and decreased ATP production. At dose of 1%, Lime extract significantly decreased DNA damage (30%, P<0.05) and increased mitochondrial ATP production (by 65%, P<0.05).

Lime extract works in & out of skin to fight against pollution and reduce cell damage.

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